2025, Vol. 6, Issue 2, Part A
Toxicological impact of lead acetate on the development and viability of Drosophila melanogaster and the protective role of Vitamin C
Author(s): Tanuja N, Sinchana M, Shravani MNR, S Priyanka Rani, Sindhu K and Shakunthala V
Abstract: Lead acetate (Pb(CH₃COO)₂) remains a pervasive environmental contaminant, posing developmental and neurological risks across taxa. Using Drosophila melanogaster, we quantified dose‑dependent effects of lead (300-500 ppm) on survival, developmental timing, and adult morphology, and tested whether dietary vitamin C (5 mM) mitigates toxicity. Lead exposure delayed pupation by up to 26 h, reduced larval survival (χ² = 21.5, p < 0.001). Vitamin C co‑supplementation improved survival by 32% at 500 ppm and normalized malondialdehyde and superoxide‑dismutase levels. These results support vitamin C as a practical dietary intervention in lead‑polluted settings [1-4].
DOI: 10.33545/27080013.2025.v6.i2a.229
Pages: 27-28 | Views: 559 | Downloads: 151
Download Full Article: Click Here
How to cite this article:
Tanuja N, Sinchana M, Shravani MNR, S Priyanka Rani, Sindhu K, Shakunthala V. Toxicological impact of lead acetate on the development and viability of Drosophila melanogaster and the protective role of Vitamin C. Acta Entomol Zool 2025;6(2):27-28. DOI: 10.33545/27080013.2025.v6.i2a.229
