Acta Entomology and Zoology
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P-ISSN: 2708-0013, E-ISSN: 2708-0021

2024, Vol. 5, Issue 1, Part C

Evaluation of oil vaccines immunity with challenges of Newcastle disease virus in Layer


Author(s): Qayssar Obaid Muhammed and Raed Hussain Salih Rabee

Abstract: The research focused on analyzing the immune reaction of layer hens to an inactivated oil-emulsion Newcastle disease virus vaccine with a new fine spray vaccination strategy, examining passive antibody durability in layer hens, and evaluating protection effectiveness against different virus strains. Approach: In this study, 200 Lohmann Brown chicks that were 1 day old were divided into two groups of 50 chicks each through random selection. Group 1 was given the vaccine via injection three times at 8, 70, and 115 days old, as well as through a spray on the same day. The control group did not receive any vaccinations. 20 days post vaccination, specimens were collected from chickens vaccinated at 30, 50, 70, 90, 110, 130, 150, 170, and 200 days old.Findings: All chickens had protective antibodies in 10 serum samples, with the most elevated haemagglutination inhibition titre observed after booster doses. There was no notable difference in antibody production in layer hens, with p value greater than 0.05.The research demonstrated that the implemented program provided effective protection, leading the herd to achieve peak production with no issues and no deaths. Additionally, antibodies passed down from the mother were present up to the age of 5 days, showing the amount of immunity received before vaccination. During the examination of the deceased birds infected with the virus, distinct lesions like swollen tracheal membranes and petechial and necrotic haemorrhages in the proventriculus were identified.In conclusion, this research indicates that administering subsequent live virus vaccine through fine spray route immunization is necessary for effectively preventing velogenic viscerotropic Newcastle disease infection. The findings also emphasize the significance of creating successful vaccination strategies and methods to boost defense against ND in layer hens.

DOI: 10.33545/27080013.2024.v5.i1c.144

Pages: 238-240 | Views: 248 | Downloads:

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Acta Entomology and Zoology
How to cite this article:
Qayssar Obaid Muhammed, Raed Hussain Salih Rabee. Evaluation of oil vaccines immunity with challenges of Newcastle disease virus in Layer. Acta Entomol Zool 2024;5(1):238-240. DOI: 10.33545/27080013.2024.v5.i1c.144

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